P-Hydroxyacetophenone CAS 99-93-4

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  • Incoterm: FOB,CFR,CIF,EXW,FCA,CPT,CIP
  • Min: 10 Gram
  • Delivery: 7 Days
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  • Port: Shanghai Port, Qingdao Port

Name: P-Hydroxyacetophenone

Cas: 99-93-4

Purity: 99%

MOQ: 1KG

Basic Info

P-Hydroxyacetophenone, also known as 4-hydroxyacetophenone, 4-acetylphenol, acetaminophen, 4-hydroxyphenylmethyl ketone, commonly known as needle like phenol, is a white needle shaped crystal at room temperature, flammable, easily soluble in hot water, methanol, ethanol, ether, acetone, benzene, and insoluble in petroleum ether. P-Hydroxyacetophenone naturally exists in the stems and leaves of the Asteraceae plant Artemisia scoparia, as well as in the roots of plants such as Artemisia scoparia and Caryophyllaceae plants such as Panax notoginseng.

P-Hydroxyacetophenone itself is a choleretic drug commonly used as an adjuvant in the treatment of cholecystitis and acute/chronic jaundice hepatitis, but its application must follow medical advice. In addition, P-Hydroxyacetophenone is also a raw material for fine chemical synthesis, commonly used in the synthesis of fragrances.

Due to the presence of hydroxyl and ketone groups on the benzene ring in P-Hydroxyacetophenone molecules, it is often used as an intermediate in organic synthesis to react with other compounds to synthesize many important substances.

Product Introduction

P-Hydroxyacetophenone Chemical Properties
Melting point 132-135 °C(lit.)
Boiling point 147-148 °C3 mm Hg(lit.)
density 1.109
vapor pressure 0.002Pa at 20℃
refractive index 1.5577 (estimate)
FEMA 4330 | 4-HYDROXYACETOPHENONE
Fp 166 °C
storage temp. Store below +30°C.
solubility methanol: 0.1 g/mL, clear
form Crystalline Powder
pka8.05(at 25℃)
color Almost white to beige
Specific Gravity1.109
Odorat 10.00 % in dipropylene glycol. mild sweet hawthorn balsam mimosa
Odor Typefloral
Water Solubility 10 g/L (22 ºC)
JECFA Number2040
BRN 774355

Product Packaging

P-Hydroxyacetophenone

1. Pharmacological effects

Anti-inflammatory effect

P-Hydroxyacetophenone has certain anti-inflammatory activity and can inhibit the release of inflammatory factors. It is used as an excipient or intermediate for some drugs.

Antibacterial activity

Studies have shown that P-Hydroxyacetophenone has a certain inhibitory effect on certain bacteria and fungi, and therefore can be added as an antibacterial ingredient in skin preparations.

Sedative effects and analgesic effects

Although there is not much research, certain in vivo experiments have shown a certain sedative and analgesic trend, which may be related to the effect of P-Hydroxyacetophenone on neurotransmitters.

2.Cosmetics Application 

Skin conditioner

P-Hydroxyacetophenone can help soothe the skin, reduce redness and sensitivity, and is commonly used in sensitive skin care products as a soothing and calming ingredient.

The Anti-Aging Treatment

It can reduce skin damage caused by environmental factors, as well as capture free radicals.

Formula stabilizer

P-Hydroxyacetophenone has certain antioxidant and stabilizing effects, which can help improve the preservation and stability of products.

3.Additives and flavors for food

In the spice industry, P-Hydroxyacetophenone is used as a synthetic intermediate for the production of certain aroma compounds.

It has a mild vanilla flavor that can be used to flavor other foods.

4. Chemical Synthesis Applications

P-Hydroxyacetophenone is an important intermediate for the synthesis of many drugs and fragrances.

Often used as a pre-cursor for the synthesis natural products, such as alkaloids and flavonoids.

Related References

Manufacturer of P-Hydroxyacetophenone

Company Info

China Lookchemical is a professional enterprise that integrates research and development, production, and sales of new chemicals. The company was the first to specialize in providing organic intermediates. After several years of continuous efforts, especially in the fields of surfactants, feed additives, plant extracts, pesticides, industrial chemicals, etc., significant breakthroughs have been made.
 
The company adheres to the concept of “integrity management, strict quality control, customer first” and has received unanimous praise from customers at home and abroad.

At the same time, we can also provide customers with excellent transportation services. Adhere to customer centricity and integrity as the source of development, and gradually improve the company’s various systems. We are high-quality management personnel who have been engaged in chemical trade for many years, with a modern market management philosophy, and constantly explore customer market demands using flexible methods.

Cooperation Partner

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