
Name: P-Hydroxyacetophenone
Cas: 99-93-4
Purity: 99%
MOQ: 1KG
Directory Guidance on P-Hydroxyacetophenone
Chemical Structure

Basic Info
P-Hydroxyacetophenone, also known as 4-hydroxyacetophenone, 4-acetylphenol, acetaminophen, 4-hydroxyphenylmethyl ketone, commonly known as needle like phenol, is a white needle shaped crystal at room temperature, flammable, easily soluble in hot water, methanol, ethanol, ether, acetone, benzene, and insoluble in petroleum ether. P-Hydroxyacetophenone naturally exists in the stems and leaves of the Asteraceae plant Artemisia scoparia, as well as in the roots of plants such as Artemisia scoparia and Caryophyllaceae plants such as Panax notoginseng.
P-Hydroxyacetophenone itself is a choleretic drug commonly used as an adjuvant in the treatment of cholecystitis and acute/chronic jaundice hepatitis, but its application must follow medical advice. In addition, P-Hydroxyacetophenone is also a raw material for fine chemical synthesis, commonly used in the synthesis of fragrances.
Due to the presence of hydroxyl and ketone groups on the benzene ring in P-Hydroxyacetophenone molecules, it is often used as an intermediate in organic synthesis to react with other compounds to synthesize many important substances.
Product Introduction
P-Hydroxyacetophenone Chemical Properties |
Melting point | 132-135 °C(lit.) |
Boiling point | 147-148 °C3 mm Hg(lit.) |
density | 1.109 |
vapor pressure | 0.002Pa at 20℃ |
refractive index | 1.5577 (estimate) |
FEMA | 4330 | 4-HYDROXYACETOPHENONE |
Fp | 166 °C |
storage temp. | Store below +30°C. |
solubility | methanol: 0.1 g/mL, clear |
form | Crystalline Powder |
pka | 8.05(at 25℃) |
color | Almost white to beige |
Specific Gravity | 1.109 |
Odor | at 10.00 % in dipropylene glycol. mild sweet hawthorn balsam mimosa |
Odor Type | floral |
Water Solubility | 10 g/L (22 ºC) |
JECFA Number | 2040 |
BRN | 774355 |
Product Name | P-Hydroxyacetophenone |
brand | China Lookchemical |
Specification | 99% |
MOQ | 1KG |
Storage conditions | Store in cool & dry place, Keep away from strong light and heat. |
Sample | Available |
Product Packaging

1. Pharmacological effects
Anti-inflammatory effect
P-Hydroxyacetophenone has certain anti-inflammatory activity and can inhibit the release of inflammatory factors. It is used as an excipient or intermediate for some drugs.
Antibacterial activity
Studies have shown that P-Hydroxyacetophenone has a certain inhibitory effect on certain bacteria and fungi, and therefore can be added as an antibacterial ingredient in skin preparations.
Sedative effects and analgesic effects
Although there is not much research, certain in vivo experiments have shown a certain sedative and analgesic trend, which may be related to the effect of P-Hydroxyacetophenone on neurotransmitters.
2.Cosmetics Application
Skin conditioner
P-Hydroxyacetophenone can help soothe the skin, reduce redness and sensitivity, and is commonly used in sensitive skin care products as a soothing and calming ingredient.
The Anti-Aging Treatment
It can reduce skin damage caused by environmental factors, as well as capture free radicals.
Formula stabilizer
P-Hydroxyacetophenone has certain antioxidant and stabilizing effects, which can help improve the preservation and stability of products.
3.Additives and flavors for food
In the spice industry, P-Hydroxyacetophenone is used as a synthetic intermediate for the production of certain aroma compounds.
It has a mild vanilla flavor that can be used to flavor other foods.
4. Chemical Synthesis Applications
P-Hydroxyacetophenone is an important intermediate for the synthesis of many drugs and fragrances.
Often used as a pre-cursor for the synthesis natural products, such as alkaloids and flavonoids.
Related References
Wikipedia-P-Hydroxyacetophenone
Manufacturer of P-Hydroxyacetophenone
China Lookchemical is based in Shandong, serves the whole country, faces the world, and is determined to become an excellent supplier and service provider in the chemical industry.
As a top manufacturer of surfactant,cosmetic raw materials, disinfectants, flavors, and fragrances in China, we are committed to producing high-quality products and have won high praise from customers all over the world.
In the next 10 years or even longer, Lookchemical will always adhere to the tenet of quality first and reputation first, and devote itself to providing customers with thoughtful and perfect services.
As a professional P-Hydroxyacetophenone manufacturer, Look Chemical has served more than 6,000 customers around the world. Because of our high-quality products and professional services, we have won high praise from most of our customers.
Pre-Sales Service
*The company cooperates with research institutes. We strictly control the process of raw materials up to the finished product.
*Dedicated to serving customers first, we provide reasonable prices, high quality products and timely delivery and follow-up services.
* Timely reply and 24 hours online, the professional team will provide you with the most favorable prices and high-quality products.
* The sample supports testing and inspection.
* Each batch of products will be tested to ensure that its quality meets user needs.
*Packaging can also be made according to customer requirements.
*Any inquiries will be answered by our relevant personnel within 24 hours.
*We will provide you with commercial invoice, packing list, packing list, COA, health certificate and certificate of origin if you need it. If your market has other special requirements, please let us know.
After-Sales Service
*We will monitor the logistics information in real time and will share the information with you.
* You can consult us at any time if you have any questions about the product, and we will answer you in time.
*If you have any questions about the product, you can report it to us, we will deal with it in time for you, and the product can be returned.
To ensure the convenience of clients,we always set accurate reply for crucial question.Clients will get answer by inputting “keywords”to help clients solve relevant questions.
DO YOU ACCEPT SAMPLE ORDER?
We will make samples before mass production. After the samples are approved by the department and users, we will start mass production. During the production process, we will carry out 100% inspection, and then carry out random inspection before packaging.
WHAT’S YOUR MOQ?
Our MOQ is 1kg. But usually we can also accept a smaller quantity, such as 100g, if you need it, provided that the sample fee is 100% paid.
IS THERE A DISCOUNT?
Different quantity has different discount.
HOW TO CONFIRM WHETHER THE PRODUCT QUALITY MEETS OUR NEEDS BEFORE PLACING AN ORDER?
You can consult us to get free samples of some products, you only need to pay the freight or arrange express delivery to us and get the samples. You can send us the product specifications and requirements you need, and we will manufacture products according to your requirements.
DO YOU SUPPLY PRODUCT REPORT?
Yes. We’ll give you product analysis report before shipping.
LEARN MORE ABOUT US
Shandong Look Chemical
1. For products ≤50kg, we recommend using express delivery, which is usually called DDU service (discounted, convenient).
2. For products ≤500kg, we generally recommend air freight, which is usually called FOB, CFR or CIF service (fast and efficient).
3. For products >500kg, we generally recommend shipping by sea, which is usually called FOB, CFR or CIF service (economical, safe).
4. For high-value products, please choose air or express to ensure the safety of product transportation.
Company Info
At the same time, we can also provide customers with excellent transportation services. Adhere to customer centricity and integrity as the source of development, and gradually improve the company’s various systems. We are high-quality management personnel who have been engaged in chemical trade for many years, with a modern market management philosophy, and constantly explore customer market demands using flexible methods.

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