Name: 1 4-Dithiane
Cas: 505-29-3
Purity: 99%
MOQ: 1KG
Directory Guidance on 1 4-Dithiane
Chemical Structure
Basic Info
Basic properties: The 1,4-dithiane is an organic compound containing sulfur with the formula C 4H 8S 2. It consists of two sulfur atoms, four alternating methylene group (-CH 2 -), and a six-membered ring. 1,4-Dithiane can be a liquid or crystal with a pungent smell similar to that of thioethers. It is not soluble in water, but is easily soluble in organic solutions. This is a common multifunctional building block used in organic synthesis.
Chemical properties: 1,4-Dithiane’s sulfur atoms give it strong coordination and reduceibility. It is a good precursor for metal ligands, or it can be used in sulfide reaction. In acidic conditions the cyclic structure can be opened, producing derivatives such as 1,2-ethanedithiol. Through oxidation, it can be converted into cyclic sulfur compounds and sulfones.
Applications: 1,4 Dithianes can be used to synthesize thiocarboxylic acids, heterocyclic compounds, and polymer materials. In coordination chemistry, 1,4 Dithianes are used as chelating agents in order to form complexes with transition metals such as palladium and platinum. Derivatives of dithianes are used in materials science and medicine.
Product Introduction
| 1 4-Dithiane Chemical Properties |
| Melting point | 107-113 °C (lit.) |
| Boiling point | 200 °C (lit.) |
| density | 1.062 (estimate) |
| refractive index | 1.5981 (estimate) |
| FEMA | 3831 | 1,4-DITHIANE |
| storage temp. | 2-8°C |
| solubility | Chloroform (Sparingly), DMSO (Slightly) |
| form | solid |
| Odor | at 0.10 % in propylene glycol. sulfurous solvent garlic onion pyridine |
| Odor Type | seafood |
| JECFA Number | 456 |
| Stability: | Stable. Incompatible with strong oxidizing agents. Probably combustible. |
Product Nature
Specification
Product Nature
Product Name | 1 4-Dithiane |
brand | China Lookchemical |
Specification | 99% |
MOQ | 1KG |
Storage conditions | Store in cool & dry place, Keep away from strong light and heat. |
Sample | Available |
Specification
Technical indicators | ||
thing | index | Measurement methods |
Appearance | 25°C white granular or flake-like solid waxy substance with fat smell | |
Relative density: | 0.81（60℃） | |
Freezing point (℃) | 48-51 | |
Flash point (℃): | 150 | |
Solubility: | Insoluble in water, soluble in organic solvents such as ethanol | |
Acid value (KOH mg/g) | ≤0.1 | GB/T 16451 |
Saponification value (KOH mg/g) | ≤0.5 | GB/T 16451 |
Iodine value (I2g/100g) | ≤0.5 | GB/T 16451 |
Hydroxyl value (KOH mg/g) | 225-235 | GB/T 16451 |
Alkane content % | ≤1.0 | GB/T 16451 |
Carbon chain distribution % | GB/T 16451 | |
C14 alcohol | 0-1 | |
C16 alcohol | ≥98 | |
C18 alcohol | 0-1 | |
color | ≤10 | GB/T 9282 |
Melting point °C | 48-51 | GB/T 617 |
Product Packaging
Main purpose
1. Protective reagents in organic synthesis
1,4-Dithiane is an important synthetic intermediate in organic chemistry, particularly used as a protecting group for carbonyl compounds (aldehydes and ketones).
One key use of it in synthesis is to construct 1,3-dithioacetal structures (dithiolane), which are used to temporarily “hide” the carbonyl groups of aldehydes and ketones, avoiding side reactions in subsequent reactions.
2. Umkehr reaction (reverse reaction) and C-C bond formation reaction
After lithiation (generating a negative ion), 1,4-dithiene can act as a C1 synthesizer to form new carbon carbon bonds, especially when constructing more complex molecular frameworks.
Used as a nucleophilic reagent after deprotonation
Used for carbon chain extension in various cross coupling reactions
3. Synthesis of intermediates for various heterocyclic or thio compounds
Due to the excellent departure and coordination abilities of sulfur atoms in the 1,4-Dithiane structure, 1,4-Dithiane is commonly used to synthesize the following types of compounds: sulfur-containing heterocycles such as thiophene, thiazole, etc. 1,4-Dithiane is used as a ligand to participate in metal organic chemical reactions and prepare high-energy materials
4. Pharmaceutical chemistry and pesticide synthesis intermediates
In the modification of drug molecular structures, sulfur-containing groups can improve the lipid solubility and metabolic stability of molecules. 1,4-Dithiane can introduce these sulfur-containing structures for the design of antibacterial and antifungal compounds, pesticide intermediates such as insecticides and acaricides, and as active drug scaffolds (especially in some novel heterocyclic candidate drugs)
5. Research on ligands/chelating agents
The two sulfur atoms in dithiene can coordinate with heavy metal ions to form stable chelates:
1 4-Dithiane for metal ion detection or separation, development of metal organic compound catalysts
Related References
Wikipedia-1 4-Dithiane
Manufacturer of 1 4-Dithiane
Achievements
Service
FAQ
Advice on Shipping
Achievements
China Lookchemical is based in Shandong, serves the whole country, faces the world, and is determined to become an excellent supplier and service provider in the chemical industry.
As a top manufacturer of surfactant,cosmetic raw materials, disinfectants, flavors, and fragrances in China, we are committed to producing high-quality products and have won high praise from customers all over the world.
In the next 10 years or even longer, Lookchemical will always adhere to the tenet of quality first and reputation first, and devote itself to providing customers with thoughtful and perfect services.
As a professional 1 4-Dithiane manufacturer, Look Chemical has served more than 6,000 customers around the world. Because of our high-quality products and professional services, we have won high praise from most of our customers.
Service
Pre-Sales Service
*The company cooperates with research institutes. We strictly control the process of raw materials up to the finished product.
*Dedicated to serving customers first, we provide reasonable prices, high quality products and timely delivery and follow-up services.
* Timely reply and 24 hours online, the professional team will provide you with the most favorable prices and high-quality products.
* The sample supports testing and inspection.
* Each batch of products will be tested to ensure that its quality meets user needs.
*Packaging can also be made according to customer requirements.
*Any inquiries will be answered by our relevant personnel within 24 hours.
*We will provide you with commercial invoice, packing list, packing list, COA, health certificate and certificate of origin if you need it. If your market has other special requirements, please let us know.
After-Sales Service
*We will monitor the logistics information in real time and will share the information with you.
* You can consult us at any time if you have any questions about the product, and we will answer you in time.
*If you have any questions about the product, you can report it to us, we will deal with it in time for you, and the product can be returned.
FAQ
To ensure the convenience of clients,we always set accurate reply for crucial question.Clients will get answer by inputting “keywords”to help clients solve relevant questions.
DO YOU ACCEPT SAMPLE ORDER?
We will make samples before mass production. After the samples are approved by the department and users, we will start mass production. During the production process, we will carry out 100% inspection, and then carry out random inspection before packaging.
WHAT’S YOUR MOQ?
Our MOQ is 1kg. But usually we can also accept a smaller quantity, such as 100g, if you need it, provided that the sample fee is 100% paid.
IS THERE A DISCOUNT?
Different quantity has different discount.
HOW TO CONFIRM WHETHER THE PRODUCT QUALITY MEETS OUR NEEDS BEFORE PLACING AN ORDER?
You can consult us to get free samples of some products, you only need to pay the freight or arrange express delivery to us and get the samples. You can send us the product specifications and requirements you need, and we will manufacture products according to your requirements.
DO YOU SUPPLY PRODUCT REPORT?
Yes. We’ll give you product analysis report before shipping.
LEARN MORE ABOUT US
Shandong Look Chemical
Advice on Shipping
1. For products ≤50kg, we recommend using express delivery, which is usually called DDU service (discounted, convenient).
2. For products ≤500kg, we generally recommend air freight, which is usually called FOB, CFR or CIF service (fast and efficient).
3. For products >500kg, we generally recommend shipping by sea, which is usually called FOB, CFR or CIF service (economical, safe).
4. For high-value products, please choose air or express to ensure the safety of product transportation.
Company Info
China Lookchemical is a professional enterprise that integrates research and development, production, and sales of new chemicals. The company was the first to specialize in providing organic intermediates. After several years of continuous efforts, especially in the fields of surfactants, feed additives, plant extracts, pesticides, industrial chemicals, etc., significant breakthroughs have been made.
The company adheres to the concept of “integrity management, strict quality control, customer first” and has received unanimous praise from customers at home and abroad.
At the same time, we can also provide customers with excellent transportation services. Adhere to customer centricity and integrity as the source of development, and gradually improve the company’s various systems. We are high-quality management personnel who have been engaged in chemical trade for many years, with a modern market management philosophy, and constantly explore customer market demands using flexible methods.
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